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STRAP Antikörper (AA 1-350)

STRAP Reaktivität: Human WB, IP, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6148639
  • Target Alle STRAP Antikörper anzeigen
    STRAP (Serine/threonine Kinase Receptor Associated Protein (STRAP))
    Bindungsspezifität
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-350
    Reaktivität
    • 45
    • 20
    • 12
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 1
    Kaninchen
    Klonalität
    • 44
    • 1
    Polyklonal
    Konjugat
    • 25
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser STRAP Antikörper ist unkonjugiert
    Applikation
    • 38
    • 13
    • 13
    • 12
    • 9
    • 9
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
    Sequenz
    MAMRQTPLTC SGHTRPVVDL AFSGITPYGY FLISACKDGK PMLRQGDTGD WIGTFLGHKG AVWGATLNKD ATKAATAAAD FTAKVWDAVS GDELMTLAHK HIVKTVDFTQ DSNYLLTGGQ DKLLRIYDLN KPEAEPKEIS GHTSGIKKAL WCSEDKQILS ADDKTVRLWD HATMTEVKSL NFNMSVSSME YIPEGEILVI TYGRSIAFHS AVSLDPIKSF EAPATINSAS LHPEKEFLVA GGEDFKLYKY DYNSGEELES YKGHFGPIHC VRFSPDGELY ASGSEDGTLR LWQTVVGKTY GLWKCVLPEE DSGELAKPKI GFPETTEEEL EEIASENSDC IFPSAPDVKA
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human STRAP (NP_009109.3).
    Isotyp
    IgG
    Top Product
    Discover our top product STRAP Primärantikörper
  • Applikationshinweise
    WB,1:1000 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    STRAP (Serine/threonine Kinase Receptor Associated Protein (STRAP))
    Andere Bezeichnung
    STRAP (STRAP Produkte)
    Synonyme
    MAWD antikoerper, PT-WD antikoerper, UNRIP antikoerper, zgc:56677 antikoerper, zgc:77604 antikoerper, mawd antikoerper, pt-wd antikoerper, unrip antikoerper, AW557906 antikoerper, C78091 antikoerper, C79202 antikoerper, Unrip antikoerper, serine/threonine kinase receptor associated protein antikoerper, tetratricopeptide repeat domain 5 antikoerper, serine/threonine kinase receptor associated protein L homeolog antikoerper, serine/threonine kinase receptor associated protein S homeolog antikoerper, STRAP antikoerper, TTC5 antikoerper, strap antikoerper, strap.L antikoerper, strap.S antikoerper, Strap antikoerper
    Hintergrund
    The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs, the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP. STRAP plays a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.,STRAP,MAWD,PT-WD,UNRIP,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Kinase,STRAP
    Molekulargewicht
    38 kDa/39 kDa
    Gen-ID
    11171
    UniProt
    Q9Y3F4
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