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TBC1D23 Antikörper (AA 250-600)

TBC1D23 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6148882
  • Target Alle TBC1D23 Produkte
    TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
    Bindungsspezifität
    • 4
    • 1
    • 1
    • 1
    AA 250-600
    Reaktivität
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 9
    Kaninchen
    Klonalität
    • 9
    Polyklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    Dieser TBC1D23 Antikörper ist unkonjugiert
    Applikation
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    SDSKEEVIKF LENTPSSLNI EDIEDLFSLA QYYCSKTPAS FRKDNHHLFG STLLGIKDDD ADLSQALCLA ISVSEILQAN QLQGEGVRFF VVDCRPAEQY NAGHLSTAFH LDSDLMLQNP SEFAQSVKSL LEAQKQSIES GSIAGGEHLC FMGSGREEED MYMNMVLAHF LQKNKEYVSI ASGGFMALQQ HLADINVDGP ENGYGHWIAS TSGSRSSINS VDGESPNGSS DRGMKSLVNK MTVALKTKSV NVREKVISFI ENTSTPVDRM SFNLPWPDRS CTERHVSSSD RVGKPYRGVK PVFSIGDEEE YDTDEIDSSS MSDDDRKEVV NIQTWINKPD VKHHFPCKEV K
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 250-600 of human TBC1D23 (NP_001186127.1).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
    Andere Bezeichnung
    TBC1D23 (TBC1D23 Produkte)
    Synonyme
    RGD1307925 antikoerper, NS4ATP1 antikoerper, 4930451A13Rik antikoerper, AU015720 antikoerper, AU043671 antikoerper, AU043778 antikoerper, D030022P07Rik antikoerper, W51689 antikoerper, zgc:63756 antikoerper, TBC1 domain family, member 23 antikoerper, TBC1 domain family member 23 antikoerper, Tbc1d23 antikoerper, TBC1D23 antikoerper, tbc1d23 antikoerper
    Hintergrund
    Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning (By similarity. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS challenge (By similarity.,TBC1D23,NS4ATP1,TBC1D23
    Molekulargewicht
    76 kDa/78 kDa
    Gen-ID
    55773
    UniProt
    Q9NUY8
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