TBL1XR1 Antikörper (AA 1-180)

Produktnummer ABIN6148893

Produktdetails anti-TBL1XR1 Antikörper

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Bindungsspezifität: AA 1-180

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBL1XR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: MSISSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GALVPPAALI SIIQKGLQYV EAEVSINEDG TLFDGRPIES LSLIDAVMPD VVQTRQQAYR DKLAQQQAAA AAAAAAAASQ QGSAKNGENT ANGEENGAHT IANNHTDMME VDGDVEIPPN KAVVLRGHES EVFICAWNPV

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human TBL1XR1 (NP_078941.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TBL1XR1

Target: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Andere Bezeichnung: TBL1XR1 (TBL1XR1 Produkte)

Synonyme: tbl1xr1 antikoerper, zgc:63617 antikoerper, c21 antikoerper, dc42 antikoerper, ira1 antikoerper, TBLR1 antikoerper, TBL1XR1 antikoerper, wu:fc46g07 antikoerper, zgc:110312 antikoerper, C21 antikoerper, DC42 antikoerper, IRA1 antikoerper, RGD1560053 antikoerper, 8030499H02Rik antikoerper, A630076E03Rik antikoerper, AW539987 antikoerper, C230089I12Rik antikoerper, Ira1 antikoerper, transducin (beta)-like 1 X-linked receptor 1b antikoerper, transducin (beta)-like 1 X-linked receptor 1 antikoerper, transducin (beta)-like 1 X-linked receptor 1a antikoerper, transducin beta like 1 X-linked receptor 1 antikoerper, transducin (beta)-like 1X-linked receptor 1 antikoerper, tbl1xr1b antikoerper, tbl1xr1 antikoerper, tbl1xr1a antikoerper, TBL1XR1 antikoerper, Tbl1xr1 antikoerper

Hintergrund: This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.,TBL1XR1,C21,DC42,IRA1,MRD41,TBLR1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Notch Signaling Pathway,Endocrine & Metabolism,Lipid Metabolism,TBL1XR1

Molekulargewicht: 55 kDa

Gen-ID: 79718

UniProt: Q9BZK7

Pathways: Regulation of Lipid Metabolism by PPARalpha