TBL1XR1 Antikörper (AA 1-180)
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- Target Alle TBL1XR1 Antikörper anzeigen
- TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))
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Bindungsspezifität
- AA 1-180
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TBL1XR1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Sequenz
- MSISSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GALVPPAALI SIIQKGLQYV EAEVSINEDG TLFDGRPIES LSLIDAVMPD VVQTRQQAYR DKLAQQQAAA AAAAAAAASQ QGSAKNGENT ANGEENGAHT IANNHTDMME VDGDVEIPPN KAVVLRGHES EVFICAWNPV
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human TBL1XR1 (NP_078941.2).
- Isotyp
- IgG
- Top Product
- Discover our top product TBL1XR1 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))
- Andere Bezeichnung
- TBL1XR1 (TBL1XR1 Produkte)
- Hintergrund
- This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.,TBL1XR1,C21,DC42,IRA1,MRD41,TBLR1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Notch Signaling Pathway,Endocrine & Metabolism,Lipid Metabolism,TBL1XR1
- Molekulargewicht
- 55 kDa
- Gen-ID
- 79718
- UniProt
- Q9BZK7
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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