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CARD11 Antikörper (C-Term)
CARD11
Reaktivität: Human, Maus
WB, IHC (p), EIA
Wirt: Ziege
Polyclonal
unconjugated
Produktdetails anti-CARD11 Antikörper
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Target
Alle CARD11 Antikörper anzeigen
CARD11
(Caspase Recruitment Domain Family, Member 11 (CARD11))
Bindungsspezifität
Alle Epitope für CARD11 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für CARD11 Antikörper
Human, Maus
Wirt
Alle Wirte für CARD11 Antikörper
Ziege
Klonalität
Alle Klonalitäten für CARD11 Antikörper
Polyklonal
Konjugat
Alle Konjugate für CARD11 Antikörper
Dieser CARD11 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CARD11 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Sequenz
C-QRKTIWVDED QL
Spezifität
This antibody detects CARD11 / CARMA1 at C-term.
Kreuzreaktivität (Details)
Species reactivity (expected):MouseSpecies reactivity (tested):Human
Aufreinigung
Immunoaffinity chromatography
Immunogen
Synthetic peptide from C-term of human CARD11 Genename: CARD11
Top Product
Discover our top product CARD11 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Tris saline buffer, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Details zu CARD11
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Target
CARD11
(Caspase Recruitment Domain Family, Member 11 (CARD11))
Andere Bezeichnung
CARD11 / CARMA1 (CARD11 Produkte )
Synonyme
BENTA antikoerper, BIMP3 antikoerper, CARMA1 antikoerper, PPBL antikoerper, 0610008L17Rik antikoerper, 2410011D02Rik antikoerper, CARD11 antikoerper, LOC100232755 antikoerper, caspase recruitment domain family member 11 antikoerper, caspase recruitment domain family, member 11 antikoerper, caspase recruitment domain-containing protein 11 antikoerper, CARD11 antikoerper, Card11 antikoerper, LOC100550812 antikoerper, card11 antikoerper
Hintergrund
CARMA proteins belong to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. Both CARMA1 and CARMA3 associate with NEMO, the regulatory subunit of the IkK complex, thereby regulating activation of the NF-kB transcription factor. Also, gene inactivation studies showed a complete block in T and B cell immunity as well as an impaired response to LPS, indicating that CARMA1 is a critical regulator in both the adaptive and innate immune systems.Synonyms: CARD-containing MAGUK protein 3, Caspase recruitment domain-containing protein 11
Gen-ID
84433
NCBI Accession
NP_115791
UniProt
Q9BXL7
Pathways
T-Zell Rezeptor Signalweg , Fc-epsilon Rezeptor Signalübertragung , BCR Signaling
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