TWEAK Antikörper (AA 42-123)
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- Target Alle TWEAK (TNFSF12) Antikörper anzeigen
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
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Bindungsspezifität
- AA 42-123
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TWEAK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequenz
- VSLGSRASLS AQEPAQEELV AEEDQDPSEL NPQTEESQDP APFLNRLVRP RRSAPKGRKT RARRAIAAHY EVHPRPGQDG AQ
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 42-123 of human TNFSF12 (NP_003800.1).
- Isotyp
- IgG
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TWEAK (TNFSF12) (Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12))
- Andere Bezeichnung
- TNFSF12 (TNFSF12 Produkte)
- Synonyme
- APO3L antikoerper, DR3LG antikoerper, TWEAK antikoerper, Apo3l antikoerper, Dr3l antikoerper, Dr3lg antikoerper, Tweak antikoerper, TNF superfamily member 12 antikoerper, tumor necrosis factor (ligand) superfamily, member 12 antikoerper, TNFSF12 antikoerper, Tnfsf12 antikoerper
- Hintergrund
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene, such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.,TNFSF12,APO3L,DR3LG,TNLG4A,TWEAK,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Growth factor,TNF,Death Receptor Signaling Pathway,TNFSF12
- Molekulargewicht
- 27 kDa/36 kDa
- Gen-ID
- 8742
- UniProt
- O43508
- Pathways
- Apoptose
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