TOPBP1 Antikörper (AA 1253-1522)

Produktnummer ABIN6149398

Produktdetails anti-TOPBP1 Antikörper

Target: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Bindungsspezifität: AA 1253-1522

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOPBP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KIITIEETHE ELKKQYIFQL SSLNPQERID YCHLIEKLGG LVIEKQCFDP TCTHIVVGHP LRNEKYLASV AAGKWVLHRS YLEACRTAGH FVQEEDYEWG SSSILDVLTG INVQQRRLAL AAMRWRKKIQ QRQESGIVEG AFSGWKVILH VDQSREAGFK RLLQSGGAKV LPGHSVPLFK EATHLFSDLN KLKPDDSGVN IAEAAAQNVY CLRTEYIADY LMQESPPHVE NYCLPEAISF IQNNKELGTG LSQKRKAPTE KNKIKRPRVH

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1253-1522 of human TOPBP1 (NP_008958.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-TOPBP1 Antikörper (ABIN6149398)

Wang, Wang, Xin, Wang, Wang, Xu, Jia, Yue, Wang, Song: "Two novel LRR-only proteins in Chlamys farreri: Similar in structure, yet different in expression profile and pattern recognition." in: Developmental and comparative immunology, Vol. 59, pp. 99-109, (2017) (PubMed).

Details zu TOPBP1

Target: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Andere Bezeichnung: TOPBP1 (TOPBP1 Produkte)

Synonyme: RGD1562949 antikoerper, TOPBP1 antikoerper, cut5 antikoerper, F2P24.3 antikoerper, F2P24_3 antikoerper, meiosis defective 1 antikoerper, TOP2BP1 antikoerper, 1110031N14Rik antikoerper, 2810429C13Rik antikoerper, AI256758 antikoerper, D430026L04Rik antikoerper, mKIAA0259 antikoerper, TopBP1-A antikoerper, TopBP1-B antikoerper, Xmus101 antikoerper, XtopBP antikoerper, mus101 antikoerper, top2bp1 antikoerper, DNA topoisomerase II binding protein 1 antikoerper, topoisomerase (DNA) II binding protein 1 antikoerper, dna topoisomerase ii binding protein 1 (IC) antikoerper, transcription coactivator antikoerper, DNA topoisomerase II binding protein 1 L homeolog antikoerper, Topbp1 antikoerper, topbp1 antikoerper, TOPBP1 antikoerper, MEI1 antikoerper, topbp1.L antikoerper

Hintergrund: This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.,TOPBP1,TOP2BP1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Drug resistance,Topoisomerases,TOPBP1

Molekulargewicht: 170 kDa

Gen-ID: 11073

UniProt: Q92547

Pathways: Chromatin Binding