TRIM25 Antikörper (AA 100-400)

Produktnummer ABIN6149513

Produktdetails anti-TRIM25 Antikörper

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Bindungsspezifität: AA 100-400

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM25 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequenz: SPNAQVACDH CLKEAAVKTC LVCMASFCQE HLQPHFDSPA FQDHPLQPPV RDLLRRKCSQ HNRLREFFCP EHSECICHIC LVEHKTCSPA SLSQASADLE ATLRHKLTVM YSQINGASRA LDDVRNRQQD VRMTANRKVE QLQQEYTEMK ALLDASETTS TRKIKEEEKR VNSKFDTIYQ ILLKKKSEIQ TLKEEIEQSL TKRDEFEFLE KASKLRGIST KPVYIPEVEL NHKLIKGIHQ STIDLKNELK QCIGRLQEPT PSSGDPGEHD PASTHKSTRP VKKVSKEEKK SKKPPPVPAL P

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-400 of human TRIM25 (NP_005073.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-TRIM25 Antikörper (ABIN6149513)

Lian, Zang, Wei, Ye, Hu, Chen, Zhang, Guo, Lei, Yang, Luo, Li, Shu: "The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors." in: Immunity, Vol. 49, Issue 3, pp. 438-448.e5, (2018) (PubMed).

Details zu TRIM25

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Andere Bezeichnung: TRIM25 (TRIM25 Produkte)

Hintergrund: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.,TRIM25,EFP,RNF147,Z147,ZNF147,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Ubiquitin,TRIM25

Molekulargewicht: 70 kDa

Gen-ID: 7706

UniProt: Q14258