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CXCR4 Antikörper (Extracellular Domain, N-Term)
CXCR4
Reaktivität: Human, Maus, Xenopus laevis
WB, IHC (p), EIA
Wirt: Ziege
Polyclonal
unconjugated
Produktdetails anti-CXCR4 Antikörper
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Target
Alle CXCR4 Antikörper anzeigen
CXCR4
(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
Bindungsspezifität
Alle Epitope für CXCR4 Antikörper
AA 14-40, Extracellular Domain, N-Term
Reaktivität
Alle Reaktivitäten für CXCR4 Antikörper
Human, Maus, Xenopus laevis
Wirt
Alle Wirte für CXCR4 Antikörper
Ziege
Klonalität
Alle Klonalitäten für CXCR4 Antikörper
Polyklonal
Konjugat
Alle Konjugate für CXCR4 Antikörper
Dieser CXCR4 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CXCR4 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Sequenz
YSEEVGSGDY DSNKEPCFRD ENVHFNR
Spezifität
This antibody binds to CXCR4 receptor on Mouse spleen leukocytes as determined by Immunocytochemistry.
Kreuzreaktivität (Details)
Species reactivity (expected):Xenopus, Human. Species reactivity (tested):Mouse
Aufreinigung
Immunoaffinity Chromatography
Immunogen
Sequence corresponding to the N-terminal extracellular domain of Mouse CXCR4 receptor. Epitope: aa14-40 Genename: CXCR4
Top Product
Discover our top product CXCR4 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
PBS, 0.09 % Sodium Azide, 1 mg/mL BSA
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu CXCR4
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Target
CXCR4
(Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
Andere Bezeichnung
CD184 / CXCR4 (CXCR4 Produkte )
Synonyme
CD184 antikoerper, D2S201E antikoerper, FB22 antikoerper, HM89 antikoerper, HSY3RR antikoerper, LAP3 antikoerper, LCR1 antikoerper, LESTR antikoerper, NPY3R antikoerper, NPYR antikoerper, NPYRL antikoerper, NPYY3R antikoerper, WHIM antikoerper, Cmkar4 antikoerper, PB-CKR antikoerper, PBSF/SDF-1 antikoerper, Sdf1r antikoerper, CXC-R4-B antikoerper, CXCR-4-B antikoerper, cd184 antikoerper, cxcr4 antikoerper, fb22 antikoerper, hm89 antikoerper, hsy3rr antikoerper, lap3 antikoerper, lcr1 antikoerper, lestr antikoerper, npy3r antikoerper, npyr antikoerper, npyrl antikoerper, npyy3r antikoerper, xcxcr4 antikoerper, CXC-R4 antikoerper, CXCR-4 antikoerper, d2s201e antikoerper, whim antikoerper, CXC-R4-A antikoerper, CXCR-4-A antikoerper, xCXCR4 antikoerper, CXCR4 antikoerper, cb403 antikoerper, zgc:109863 antikoerper, cb824 antikoerper, C-X-C motif chemokine receptor 4 antikoerper, chemokine (C-X-C motif) receptor 4 antikoerper, C-X-C motif chemokine receptor 4 S homeolog antikoerper, C-X-C chemokine receptor type 4 antikoerper, C-X-C motif chemokine receptor 4 L homeolog antikoerper, chemokine (C-X-C motif), receptor 4b antikoerper, chemokine (C-X-C motif) receptor 4a antikoerper, CXCR4 antikoerper, Cxcr4 antikoerper, cxcr4.S antikoerper, cxcr4 antikoerper, LOC100049444 antikoerper, cxcr4.L antikoerper, cxcr4b antikoerper, cxcr4a antikoerper
Hintergrund
CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.Synonyms: C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, NPYRL, SDF1 receptor, Stromal cell-derived factor 1 receptor
Gen-ID
7852
NCBI Accession
NP_001008540
UniProt
P61073
Pathways
Regulation of Cell Size , CXCR4-mediated Signaling Events
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