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TSC1 Antikörper (AA 550-650)

TSC1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6149609
  • Target Alle TSC1 Antikörper anzeigen
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    Bindungsspezifität
    • 24
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 550-650
    Reaktivität
    • 187
    • 139
    • 53
    • 24
    • 18
    • 2
    • 1
    • 1
    Human
    Wirt
    • 301
    • 16
    • 1
    • 1
    Kaninchen
    Klonalität
    • 303
    • 16
    Polyklonal
    Konjugat
    • 113
    • 37
    • 36
    • 36
    • 32
    • 32
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser TSC1 Antikörper ist unkonjugiert
    Applikation
    • 230
    • 208
    • 91
    • 27
    • 26
    • 26
    • 15
    • 14
    • 9
    • 7
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequenz
    QAFTPIDLPC GSADESPAGD RECQTSLETS IFTPSPCKIP PPTRVGFGSG QPPPYDHLFE VALPKTAHHF VIRKTEELLK KAKGNTEEDG VPSTSPMEVL D
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 550-650 of human TSC1 (NP_000359.1).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:1000,IHC,1:50 - 1:100,IF,1:50 - 1:100
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Zheng, Zhou, Zhang, Thu, Xie, Lu, Pang, Xue, Xu, Chen, Chen, Li, Xu: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." in: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).

  • Target
    TSC1 (Tuberous Sclerosis 1 (TSC1))
    Andere Bezeichnung
    TSC1 (TSC1 Produkte)
    Synonyme
    LAM antikoerper, TSC antikoerper, hamartin antikoerper, mKIAA0243 antikoerper, tsc1 antikoerper, wu:fc38b04 antikoerper, fa99f04 antikoerper, wu:fa99f04 antikoerper, zgc:63657 antikoerper, TSC complex subunit 1 antikoerper, tuberous sclerosis 1 antikoerper, TSC complex subunit 1b antikoerper, TSC complex subunit 1a antikoerper, TSC1 antikoerper, Tsc1 antikoerper, tsc1b antikoerper, tsc1 antikoerper, tsc1a antikoerper
    Hintergrund
    This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.,TSC1,LAM,TSC,hamartin,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Cell Cycle,Cell cycle inhibitors,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Obesity,Akt downstream targets,Regulators,TSC1
    Molekulargewicht
    124 kDa/129 kDa
    Gen-ID
    7248
    UniProt
    Q92574
    Pathways
    RTK Signalweg, AMPK Signaling, Regulation of Cell Size, Tube Formation
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