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TSH receptor Antikörper (AA 21-253)

TSHR Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6149622
  • Target Alle TSH receptor (TSHR) Antikörper anzeigen
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Bindungsspezifität
    • 16
    • 16
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-253
    Reaktivität
    • 86
    • 52
    • 36
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Human
    Wirt
    • 74
    • 14
    • 1
    • 1
    Kaninchen
    Klonalität
    • 75
    • 15
    Polyklonal
    Konjugat
    • 44
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TSH receptor Antikörper ist unkonjugiert
    Applikation
    • 44
    • 40
    • 20
    • 17
    • 13
    • 13
    • 12
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    GMGCSSPPCE CHQEEDFRVT CKDIQRIPSL PPSTQTLKLI ETHLRTIPSH AFSNLPNISR IYVSIDVTLQ QLESHSFYNL SKVTHIEIRN TRNLTYIDPD ALKELPLLKF LGIFNTGLKM FPDLTKVYST DIFFILEITD NPYMTSIPVN AFQGLCNETL TLKLYNNGFT SVQGYAFNGT KLDAVYLNKN KYLTVIDKDA FGGVYSGPSL LLPLGRKSLS FETQKAPRSS MPS
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 21-253 of human TSHR (NP_001018046.1).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Yang, Yi, Zhang, He, He, Wu, Xu, Li, Fan, Zhu, Xue, Zhou: "Generation and characterization of a hypothyroidism rat model with truncated thyroid stimulating hormone receptor." in: Scientific reports, Vol. 8, Issue 1, pp. 4004, (2018) (PubMed).

  • Target
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Andere Bezeichnung
    TSHR (TSHR Produkte)
    Synonyme
    CHNG1 antikoerper, LGR3 antikoerper, hTSHR-I antikoerper, AI481368 antikoerper, hypothroid antikoerper, hyt antikoerper, pet antikoerper, TSHRA antikoerper, TSH-R antikoerper, thyroid stimulating hormone receptor antikoerper, tshr antikoerper, TSHR antikoerper, Tshr antikoerper
    Hintergrund
    The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.,TSHR,CHNG1,LGR3,hTSHR-I,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,TSHR
    Molekulargewicht
    28 kDa/30 kDa/86 kDa
    Gen-ID
    7253
    UniProt
    P16473
    Pathways
    Thyroid Hormone Synthesis
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