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TXNIP Antikörper (AA 1-166)

Name: TXNIP Antikörper (AA 1-166)
Brand: antibodies-online
SKU: ABIN6149733
Price: 722.37 EUR
Availability: InStock

TXNIP Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

Effects of PU on the high glucose-induced inflammasome signaling pathway. (TXNIP Antikörper (AA 1-166))

Immunofluorescence analysis of PC-12 cells using TXNIP antibody (ABIN6130776, ABIN6149733, ABIN6149734 and ABIN6224986) at dilution of 1:100. (TXNIP Antikörper (AA 1-166))

Western blot analysis of extracts of Rat uterus, using TXNIP antibody (ABIN6130776, ABIN6149733, ABIN6149734 and ABIN6224986) at 1:890 dilution. (TXNIP Antikörper (AA 1-166))

Immunofluorescence analysis of U2OS cells using TXNIP antibody (ABIN6130776, ABIN6149733, ABIN6149734 and ABIN6224986) at dilution of 1:100. (TXNIP Antikörper (AA 1-166))

Immunofluorescence analysis of NIH/3T3 cells using TXNIP antibody (ABIN6130776, ABIN6149733, ABIN6149734 and ABIN6224986) at dilution of 1:100. (TXNIP Antikörper (AA 1-166))

5 Abbildungen

(1 reference)

Produktnummer ABIN6149733

Datenblatt (PDF)

Target Alle TXNIP Antikörper anzeigen

TXNIP (Thioredoxin Interacting Protein (TXNIP))
Bindungsspezifität
16

9

8

5

5

4

3

1

1

1

1

1

1

1

1

1
AA 1-166
Reaktivität
62

48

33

5

4

4

3

3

2

2

1

1
Human
Wirt
71

5
Kaninchen
Passende Sekundärantikörper
Klonalität
63

13
Polyklonal
Konjugat
30

7

6

5

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Dieser TXNIP Antikörper ist unkonjugiert
Applikation
52

27

15

14

14

8

8

5

3

3

3

1

1
Western Blotting (WB), Immunofluorescence (IF)

Sequenz

MVMFKKIKSF EVVFNDPEKV YGSGEKVAGR VIVEVCEVTR VKAVRILACG VAKVLWMQGS QQCKQTSEYL RYEDTLLLED QPTGENEMVI MRPGNKYEYK FGFELPQGPL GTSFKGKYGC VDYWVKAFLD RPSQPTQETK KNFEVVDLVD VNTPDLMAPV SAKKEK

Kreuzreaktivität

Human, Maus, Ratte

Produktmerkmale

Polyclonal Antibodies

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human TXNIP (NP_006463.3).

Isotyp

IgG

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anti-Thioredoxin Interacting Protein (TXNIP) (AA 32-367) antibody
TXNIP Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibody
TXNIP Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Schaf WB Wirt: Kaninchen Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-30), (N-Term) antibody
TXNIP Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB41554 unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 116-145) antibody
TXNIP Reaktivität: Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB30652 unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (Internal Region) antibody
TXNIP Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 101-200) antibody
TXNIP Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibody
TXNIP Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Schaf, Affe, Fledermaus, Schwein, Xenopus laevis WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 299-381) antibody
TXNIP Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Thioredoxin Interacting Protein (TXNIP) (AA 121-170) antibody
TXNIP Reaktivität: Human, Hund, Rind (Kuh), Affe WB Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB,1:200 - 1:2000,IF,1:50 - 1:200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Zhang, Zhang, Deng, Zhang, Xu: "Baicalin protects AML-12 cells from lipotoxicity via the suppression of ER stress and TXNIP/NLRP3 inflammasome activation." in: Chemico-biological interactions, Vol. 278, pp. 189-196, (2017) (PubMed).
Target

TXNIP (Thioredoxin Interacting Protein (TXNIP))

Andere Bezeichnung

TXNIP (TXNIP Produkte)

Hintergrund

This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.,TXNIP,ARRDC6,EST01027,HHCPA78,THIF,VDUP1,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Carbohydrate metabolism,TXNIP

Molekulargewicht

37 kDa/43 kDa

Gen-ID

10628

UniProt

Q9H3M7

Pathways

Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome