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TXNRD2 Antikörper (AA 100-310)

TXNRD2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6149741
  • Target Alle TXNRD2 Antikörper anzeigen
    TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))
    Bindungsspezifität
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-310
    Reaktivität
    • 23
    • 13
    • 12
    • 2
    Human
    Wirt
    • 19
    • 3
    • 1
    Kaninchen
    Klonalität
    • 19
    • 4
    Polyklonal
    Konjugat
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TXNRD2 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 10
    • 9
    • 4
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequenz
    AALLGGLIQD APNYGWEVAQ PVPHDWRKMA EAVQNHVKSL NWGHRVQLQD RKVKYFNIKA SFVDEHTVCG VAKGGKEILL SADHIIIATG GRPRYPTHIE GALEYGITSD DIFWLKESPG KTLVVGASYV ALECAGFLTG IGLDTTIMMR SIPLRGFDQQ MSSMVIEHMA SHGTRFLRGC APSRVRRLPD GQLQVTWEDS TTGKEDTGTF D
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 100-310 of human Thioredoxin reductase 2 (Thioredoxin reductase 2 (TXNRD2 ) ) (NP_006431.2).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))
    Andere Bezeichnung
    TXNRD2 (TXNRD2 Produkte)
    Synonyme
    CG11401 antikoerper, Dm-TrxR antikoerper, DmTrx antikoerper, DmTrxR-2 antikoerper, Dmel\\CG11401 antikoerper, Trxr2 antikoerper, trxr-2 antikoerper, SELZ antikoerper, TR antikoerper, TR-BETA antikoerper, TR3 antikoerper, TRXR2 antikoerper, AA118373 antikoerper, ESTM573010 antikoerper, TGR antikoerper, Tr3 antikoerper, Trxrd2 antikoerper, thioredoxin reductase 2 antikoerper, Trxr-2 antikoerper, TXNRD2 antikoerper, Txnrd2 antikoerper
    Hintergrund
    The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms, including a few localized in the cytosol and some lacking the C-terminal Sec residue, have been found for this gene.,TXNRD2,SELZ,TR,TR-BETA,TR3,TRXR2,Cell Biology & Developmental Biology,Endocrine & Metabolism,TXNRD2
    Molekulargewicht
    30 kDa/46 kDa/53 kDa/56 kDa
    Gen-ID
    10587
    UniProt
    Q9NNW7
    Pathways
    Cell RedoxHomeostasis
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