UBE2F Antikörper (AA 1-185)

Produktnummer ABIN6149794

Produktdetails anti-UBE2F Antikörper

Target: UBE2F (Ubiquitin-Conjugating Enzyme E2F (UBE2F))

Bindungsspezifität: AA 1-185

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2F Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MLTLASKLKR DDGLKGSRTA ATASDSTRRV SVRDKLLVKE VAELEANLPC TCKVHFPDPN KLHCFQLTVT PDEGYYQGGK FQFETEVPDA YNMVPPKVKC LTKIWHPNIT ETGEICLSLL REHSIDGTGW APTRTLKDVV WGLNSLFTDL LNFDDPLNIE AAEHHLRDKE DFRNKVDDYI KRYAR

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human UBE2F (NP_542409.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu UBE2F

Target: UBE2F (Ubiquitin-Conjugating Enzyme E2F (UBE2F))

Andere Bezeichnung: UBE2F (UBE2F Produkte)

Synonyme: NCE2 antikoerper, 2510010F15Rik antikoerper, AI851109 antikoerper, RGD1307608 antikoerper, zgc:77005 antikoerper, ubiquitin conjugating enzyme E2 F (putative) antikoerper, NEDD8-conjugating enzyme UBE2F antikoerper, ubiquitin-conjugating enzyme E2F (putative) antikoerper, ubiquitin conjugating enzyme E2F (putative) S homeolog antikoerper, UBE2F antikoerper, Tsp_01616 antikoerper, ube2f antikoerper, ube2f.S antikoerper, Ube2f antikoerper

Hintergrund: Ube2F is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for conjugation of Nedd8 to protein substrates. Neddylation is initiated by activating Nedd8 by the Nedd8 activating enzyme APPBP1/UBA3. Cullin is a well-known substrate for Neddylation. When NEDD8 is covalently bonded to the CRL, it stimulates its E3 Ub ligase activity. A new approach to cancer therapy involves hindering the Nedd8 conjugation pathway through inhibition of the NAE1/UBA3 enzyme.,UBE2F,NCE2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,UBE2F

Molekulargewicht: 11 kDa/13 kDa/17 kDa/18 kDa/21 kDa/23 kDa

Gen-ID: 140739

UniProt: Q969M7