ube3a Antikörper (AA 300-590)

Produktnummer ABIN6149835

Produktdetails anti-ube3a Antikörper

Target: ube3a (Ubiquitin Protein Ligase E3A (ube3a))

Bindungsspezifität: AA 300-590

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ube3a Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: KLIRLWSKYN ADQIRRMMET FQQLITYKVI SNEFNSRNLV NDDDAIVAAS KCLKMVYYAN VVGGEVDTNH NEEDDEEPIP ESSELTLQEL LGEERRNKKG PRVDPLETEL GVKTLDCRKP LIPFEEFINE PLNEVLEMDK DYTFFKVETE NKFSFMTCPF ILNAVTKNLG LYYDNRIRMY SERRITVLYS LVQGQQLNPY LRLKVRRDHI IDDALVRLEM IAMENPADLK KQLYVEFEGE QGVDEGGVSK EFFQLVVEEI FNPDIGMFTY DESTKLFWFN PSSFETEGQF T

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-590 of human UBE3A (NP_570853.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ube3a

Target: ube3a (Ubiquitin Protein Ligase E3A (ube3a))

Andere Bezeichnung: UBE3A (ube3a Produkte)

Synonyme: ANCR antikoerper, AS antikoerper, E6-AP antikoerper, EPVE6AP antikoerper, HPVE6A antikoerper, DDBDRAFT_0188760 antikoerper, DDBDRAFT_0302447 antikoerper, DDB_0188760 antikoerper, DDB_0302447 antikoerper, ube3a antikoerper, im:7140733 antikoerper, zgc:92173 antikoerper, 4732496B02 antikoerper, 5830462N02Rik antikoerper, A130086L21Rik antikoerper, Hpve6a antikoerper, mKIAA4216 antikoerper, As antikoerper, CG6190 antikoerper, Dmel\\CG6190 antikoerper, Dube3a antikoerper, UBE3A antikoerper, dUBE3A antikoerper, das antikoerper, dube3A antikoerper, dube3a antikoerper, MGC69536 antikoerper, UME3A antikoerper, ubiquitin protein ligase E3A antikoerper, ubiquitin-protein ligase E3A antikoerper, Ubiquitin protein ligase E3A antikoerper, ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) S homeolog antikoerper, ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) antikoerper, UBE3A antikoerper, ube3a antikoerper, LOC100194730 antikoerper, Ube3a antikoerper, ube3a.S antikoerper, Eint_040430 antikoerper

Hintergrund: This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined.,UBE3A,ANCR,AS,E6-AP,EPVE6AP,HPVE6A,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Neuroscience,Neurodegenerative Diseases,UBE3A

Molekulargewicht: 97 kDa/100 kDa

Gen-ID: 7337

UniProt: Q05086

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway