RENT2/UPF2 Antikörper (AA 1153-1272)

Produktnummer ABIN6149941

Produktdetails anti-RENT2/UPF2 Antikörper

Target: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Bindungsspezifität: AA 1153-1272

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RENT2/UPF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GPPLGGGEGE AESADTMPFV MLTRKGNKQQ FKILNVPMSS QLAANHWNQQ QAEQEERMRM KKLTLDINER QEQEDYQEML QSLAQRPAPA NTNRERRPRY QHPKGAPNAD LIFKTGGRRR

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1153-1272 of human UPF2 (NP_542166.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RENT2/UPF2

Target: RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))

Andere Bezeichnung: UPF2 (UPF2 Produkte)

Synonyme: HUPF2 antikoerper, RENT2 antikoerper, smg-3 antikoerper, UPF2, regulator of nonsense mediated mRNA decay antikoerper, UPF2 regulator of nonsense transcripts homolog (yeast) antikoerper, UPF2 antikoerper, Upf2 antikoerper, upf2 antikoerper

Hintergrund: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein.,UPF2,HUPF2,RENT2,smg-3,Epigenetics & Nuclear Signaling,UPF2

Molekulargewicht: 66 kDa/147 kDa

Gen-ID: 26019

UniProt: Q9HAU5