USP7 Antikörper (AA 206-1102)

Produktnummer ABIN6150031

Produktdetails anti-USP7 Antikörper

Target: USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))

Bindungsspezifität: AA 206-1102

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: DSKKHTGYVG LKNQGATCYM NSLLQTLFFT NQLRKAVYMM PTEGDDSSKS VPLALQRVFY ELQHSDKPVG TKKLTKSFGW ETLDSFMQHD VQELCRVLLD NVENKMKGTC VEGTIPKLFR GKMVSYIQCK EVDYRSDRRE DYYDIQLSIK GKKNIFESFV DYVAVEQLDG DNKYDAGEHG LQEAEKGVKF LTLPPVLHLQ LMRFMYDPQT DQNIKINDRF EFPEQLPLDE FLQKTDPKDP ANYILHAVLV HSGDNHGGHY VVYLNPKGDG KWCKFDDDVV SRCTKEEAIE HNYGGHDDDL SVRHCTNAYM LVYIRESKLS EVLQAVTDHD IPQQLVERLQ EEKRIEAQKR KERQEAHLYM QVQIVAEDQF CGHQGNDMYD EEKVKYTVFK VLKNSSLAEF VQSLSQTMGF PQDQIRLWPM QARSNGTKRP AMLDNEADGN KTMIELSDNE NPWTIFLETV DPELAASGAT LPKFDKDHDV MLFLKMYDPK TRSLNYCGHI YTPISCKIRD LLPVMCDRAG FIQDTSLILY EEVKPNLTER IQDYDVSLDK ALDELMDGDI IVFQKDDPEN DNSELPTAKE YFRDLYHRVD VIFCDKTIPN DPGFVVTLSN RMNYFQVAKT VAQRLNTDPM LLQFFKSQGY RDGPGNPLRH NYEGTLRDLL QFFKPRQPKK LYYQQLKMKI TDFENRRSFK CIWLNSQFRE EEITLYPDKH GCVRDLLEEC KKAVELGEKA SGKLRLLEIV SYKIIGVHQE DELLECLSPA TSRTFRIEEI PLDQVDIDKE NEMLVTVAHF HKEVFGTFGI PFLLRIHQGE HFREVMKRIQ SLLDIQEKEF EKFKFAIVMM GRHQYINEDE YEVNLKDFEP QPGNMSHPRP WLGLDHFNKA PKRSRYTYLE KAIKIHN

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 206-1102 of human USP7/HAUSP (NP_003461.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu USP7

Target: USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))

Andere Bezeichnung: USP7 (USP7 Produkte)

Synonyme: CG1490 antikoerper, Dmel\\CG1490 antikoerper, USP7 antikoerper, 2210010O09Rik antikoerper, AA409944 antikoerper, AA617399 antikoerper, AU019296 antikoerper, AW548146 antikoerper, C80752 antikoerper, Hausp antikoerper, HAUSP antikoerper, TEF1 antikoerper, UBP antikoerper, Ubiquitin-specific protease 7 antikoerper, ubiquitin carboxyl-terminal hydrolase 7 antikoerper, ubiquitin specific peptidase 7 antikoerper, Usp7 antikoerper, LOC100201254 antikoerper, USP7 antikoerper

Hintergrund: The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.,USP7,HAUSP,TEF1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Ubiquitin,USP7

Molekulargewicht: 126 kDa/128 kDa

Gen-ID: 7874

UniProt: Q93009