Vinculin Antikörper (AA 767-1066)

Produktnummer ABIN6150070

Produktdetails anti-Vinculin Antikörper

Target: Vinculin (VCL)

Bindungsspezifität: AA 767-1066

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Vinculin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: AKREVENSED PKFREAVKAA SDELSKTISP MVMDAKAVAG NISDPGLQKS FLDSGYRILG AVAKVREAFQ PQEPDFPPPP PDLEQLRLTD ELAPPKPPLP EGEVPPPRPP PPEEKDEEFP EQKAGEVINQ PMMMAARQLH DEARKWSSKG NDIIAAAKRM ALLMAEMSRL VRGGSGTKRA LIQCAKDIAK ASDEVTRLAK EVAKQCTDKR IRTNLLQVCE RIPTISTQLK ILSTVKATML GRTNISDEES EQATEMLVHN AQNLMQSVKE TVREAEAASI KIRTDAGFTL RWVRKTPWYQ

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 767-1066 of human Vinculin (NP_003364.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Vinculin

Target: Vinculin (VCL)

Andere Bezeichnung: VCL (VCL Produkte)

Synonyme: CMD1W antikoerper, CMH15 antikoerper, MV antikoerper, MVCL antikoerper, VCL antikoerper, im:6902790 antikoerper, hm:zehn2160 antikoerper, DDBDRAFT_0186762 antikoerper, DDBDRAFT_0232320 antikoerper, DDB_0186762 antikoerper, DDB_0232320 antikoerper, 9430097D22 antikoerper, AA571387 antikoerper, AI462105 antikoerper, AW545629 antikoerper, CG3299 antikoerper, CT11081 antikoerper, Dmel\\CG3299 antikoerper, Dmvincp antikoerper, EG:103B4.1 antikoerper, Vin antikoerper, Vin2EF antikoerper, vinc antikoerper, LOC100228062 antikoerper, vcl-A antikoerper, vinculin antikoerper, vinculin a antikoerper, vinculin A antikoerper, Vinculin antikoerper, vinculin S homeolog antikoerper, VCL antikoerper, vcla antikoerper, vinA antikoerper, Vcl antikoerper, Vinc antikoerper, CpipJ_CPIJ013873 antikoerper, Bm1_37935 antikoerper, vcl antikoerper, vcl.S antikoerper

Hintergrund: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.,VCL,CMD1W,CMH15,HEL114,MV,MVCL,vinculin,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,Cardiovascular,Heart,Contractility,Cardiac arrhythmias,VCL

Molekulargewicht: 24 kDa/116 kDa/123 kDa

Gen-ID: 7414

UniProt: P18206

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2