WWOX Antikörper (AA 1-120)
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- Target Alle WWOX Antikörper anzeigen
- WWOX (WW Domain Containing Oxidoreductase (WWOX))
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Bindungsspezifität
- AA 1-120
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WWOX Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Sequenz
- MAALRYAGLD DTDSEDELPP GWEERTTKDG WVYYANHTEE KTQWEHPKTG KRKRVAGDLP YGWEQETDEN GQVFFVDHIN KRTTYLDPRL AFTVDDNPTK PTTRQRYDGS TTAMEILQGR
- Kreuzreaktivität
- Human, Maus
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human WWOX (NP_057457.1).
- Isotyp
- IgG
- Top Product
- Discover our top product WWOX Primärantikörper
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- Applikationshinweise
- WB,1:1000 - 1:2000,IF,1:50 - 1:200
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- WWOX (WW Domain Containing Oxidoreductase (WWOX))
- Andere Bezeichnung
- WWOX (WWOX Produkte)
- Hintergrund
- This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.,WWOX,D16S432E,EIEE28,FOR,FRA16D,HHCMA56,PRO0128,SCAR12,SDR41C1,WOX1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Growth factor,TNF,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,WWOX
- Molekulargewicht
- 4 kDa/21 kDa/23 kDa/26 kDa/35 kDa/41 kDa/46 kDa
- Gen-ID
- 51741
- UniProt
- Q9NZC7
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