ZEB1 Antikörper (AA 1-260)

Produktnummer ABIN6150422

Produktdetails anti-ZEB1 Antikörper

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Bindungsspezifität: AA 1-260

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZEB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MADGPRCKRR KQANPRRNNV TNYNTVVETN SDSDDEDKLH IVEEESVTDA ADCEGVPEDD LPTDQTVLPG RSSEREGNAK NCWEDDTGKE GQEILGPEAQ ADEAGCTVKD DECESDAENE QNHDPNVEEF LQQQDTAVIF PEAPEEDQRQ GTPEASGHDE NGTPDAFSQL LTCPYCDRGY KRFTSLKEHI KYRHEKNEDN FSCSLCSYTF AYRTQLERHM TSHKSGRDQR HVTQSGCNRK FKCTECGKAF KYKHHLKEHL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ZEB1 (NP_001167567.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-ZEB1 Antikörper (ABIN6150422)

Ju, Chen, Deng, Liu, Wang, Wang, Nie, Wang, Ding, Yao, Gui, Li, Xu, Ma, Song, Kvansakul, Zen, Zhang, Luo, Fang, Huang, Allis, Tan, Zeng, Wei, Zhao: "NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression." in: Nature communications, Vol. 8, Issue 1, pp. 928, (2018) (PubMed).

Liang, Yang, Guan, Lv, Qu, Fu, Zhao: "LncRNA UCA1 sponges miR-204-5p to promote migration, invasion and epithelial-mesenchymal transition of glioma cells via upregulation of ZEB1." in: Pathology, research and practice, Vol. 214, Issue 9, pp. 1474-1481, (2018) (PubMed).

Details zu ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Andere Bezeichnung: ZEB1 (ZEB1 Produkte)

Hintergrund: This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.,ZEB1,AREB6,BZP,DELTAEF1,FECD6,NIL2A,PPCD3,TCF8,ZFHEP,ZFHX1A,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Wnt/β-Catenin Signaling Pathway,ZEB1

Molekulargewicht: 116 kDa/122 kDa/124 kDa

Gen-ID: 6935

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation