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AIF Antikörper (AA 593-606)
AIFM1
Reaktivität: Human
WB, IF, IHC (p), EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-AIF Antikörper
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Target
Alle AIF (AIFM1) Antikörper anzeigen
AIF (AIFM1)
(Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
Bindungsspezifität
Alle Epitope für AIF Antikörper
AA 593-606
Reaktivität
Alle Reaktivitäten für AIF Antikörper
Human
Wirt
Alle Wirte für AIF Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für AIF Antikörper
Polyklonal
Konjugat
Alle Konjugate für AIF Antikörper
Dieser AIF Antikörper ist unkonjugiert
Applikation
Alle Applikationen für AIF Antikörper
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Spezifität
This antibody reacts to Apoptosis-inducing Factor (AIFM1, PDCD8).
Aufreinigung
Immunoaffinity Chromatography
Immunogen
AIFM1 antibody was raised against synthetic peptide (KDGEQHEDLNEVAK) corresponding to amino acids 593 to 606 of human AIF.
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Discover our top product AIFM1 Primärantikörper
Alternativen
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anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 131-230) antibody
AIFM1
Reaktivität: Human, Maus, Ratte, Schwein
WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
Details zu AIF
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Target
AIF (AIFM1)
(Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
Andere Bezeichnung
AIFM1 / AIF (AIFM1 Produkte )
Synonyme
AIF antikoerper, CMTX4 antikoerper, COWCK antikoerper, COXPD6 antikoerper, PDCD8 antikoerper, CG7263 antikoerper, DmAIF antikoerper, Dmel\\CG7263 antikoerper, GB16024 antikoerper, DDBDRAFT_0187853 antikoerper, DDBDRAFT_0191137 antikoerper, DDB_0187853 antikoerper, DDB_0191137 antikoerper, aif antikoerper, pdcd8 antikoerper, AIFM1 antikoerper, PCD8 antikoerper, AIFsh2 antikoerper, Hq antikoerper, Pdcd8 antikoerper, mAIF antikoerper, Aif antikoerper, zgc:91994 antikoerper, apoptosis inducing factor mitochondria associated 1 antikoerper, allograft inflammatory factor 1 antikoerper, Apoptosis inducing factor antikoerper, apoptosis-inducing factor 1, mitochondrial antikoerper, apoptosis inducing factor antikoerper, apoptosis inducing factor, mitochondria associated 1 antikoerper, apoptosis-inducing factor, mitochondrion-associated, 1 antikoerper, apoptosis-inducing factor, mitochondrion-associated 1 antikoerper, AIFM1 antikoerper, AIF1 antikoerper, AIF antikoerper, LOC412212 antikoerper, aif antikoerper, aifm1 antikoerper, Aifm1 antikoerper
Hintergrund
Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins. A novel gene, the product of which causes chromatin condensation and DNA fragmentation, was recently identified, cloned, and designated apoptosis inducing factor (AIF). Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria. AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli. AIF is highly conserved between human and mouse and widely expressed.Synonyms: Apoptosis-inducing factor 1 mitochondrial, PDCD8, Programmed cell death protein 8
Gen-ID
9131
NCBI Accession
NP_004199
UniProt
O95831
Pathways
Apoptose , Positive Regulation of Endopeptidase Activity , Cell RedoxHomeostasis , Smooth Muscle Cell Migration , Warburg Effekt
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