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Prostaglandin D2 Receptor 2 (PTGDR2) (AA 329-348) Antikörper
PTGDR2
Reaktivität: Human, Maus, Ratte
WB, IHC (p), EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails
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Target
Alle Prostaglandin D2 Receptor 2 (PTGDR2) Antikörper anzeigen
Prostaglandin D2 Receptor 2 (PTGDR2)
Bindungsspezifität
Alle Epitope für PTGDR2 Antikörper
AA 329-348
Reaktivität
Alle Reaktivitäten für PTGDR2 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für PTGDR2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für PTGDR2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für PTGDR2 Antikörper
Unkonjugiert
Applikation
Alle Applikationen für PTGDR2 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Sequenz
329-348 [DDSELGGAGS SRRRRTSSTA ]
Spezifität
This antibody reacts to G Protein-Coupled Receptor GPR44 (CRTH2) near the C-terminus.
Aufreinigung
Immunoaffinity Chromatography
Immunogen
GPR44 antibody was raised against synthetic peptide- KLH conjugated Genename: GPR44
Isotyp
IgG
Top Product
Discover our top product PTGDR2 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1,0 mg/mL
Buffer
PBS containing 0.02 % sodium azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Antigendetails
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Target
Prostaglandin D2 Receptor 2 (PTGDR2)
Andere Bezeichnung
CD294 / GPR44 (PTGDR2 Produkte )
Synonyme
CD294 antikoerper, CRTH2 antikoerper, DL1R antikoerper, DP2 antikoerper, GPR44 antikoerper, Crth2 antikoerper, Grp45 antikoerper, Ptgdr2 antikoerper, Gpr44 antikoerper, prostaglandin D2 receptor 2 antikoerper, PTGDR2 antikoerper, Ptgdr2 antikoerper
Hintergrund
GPR44, also called CRTH2, is a Prostanoid Receptor that binds prostaglandin D2. PGD2 signals through CRTH2 to induce Th2, eosinophil, and basophil chemotaxis in a G-alpha(i) dependent manner. CRTH2 may play a role in mast cell-mediated immune responses such as those involved in allergic reactions. This receptor is upregulated in activated T helper-2 (Th2) cells, peripheral blood basophils, and eosinophils, but not in Th1 lineage cells. It may be a useful marker for Th2 and Tc2 cells.Synonyms: CRTH2, Chemoattractant receptor-homologous molecule expressed on Th2 cells, DL1R, Putative G-protein coupled receptor 44
Gen-ID
11251
NCBI Accession
NP_004769
UniProt
Q9Y5Y4
Pathways
Regulation of G-Protein Coupled Receptor Protein Signaling
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