GNAQ Antikörper (Internal Region)
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- Target Alle GNAQ Antikörper anzeigen
- GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))
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Bindungsspezifität
- AA 162-175, Internal Region
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Schwein
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser GNAQ Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Sequenz
- C-NDLDRVADPA YLPT
- Spezifität
- Recognizes GNAQ / ALPHA-q (aa 162-175).
- Kreuzreaktivität (Details)
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Species reactivity (expected):Canine (Dog), Pig, Cow.
Species reactivity (tested):Human, Mouse and Rat. - Aufreinigung
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
- Immunogen
- Peptide with sequence from the internal region of the protein sequence according to NP_002063.2. Genename: GNAQ
- Top Product
- Discover our top product GNAQ Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- GNAQ (Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ))
- Abstract
- GNAQ Produkte
- Synonyme
- si:ch73-270f14.2 antikoerper, CMC1 antikoerper, G-ALPHA-q antikoerper, GAQ antikoerper, SWS antikoerper, Galphaq antikoerper, Gnaq antikoerper, g-alpha-q antikoerper, gaq antikoerper, gnaqb antikoerper, 1110005L02Rik antikoerper, 6230401I02Rik antikoerper, AA408290 antikoerper, AW060788 antikoerper, Dsk1 antikoerper, Dsk10 antikoerper, Gq antikoerper, GqI antikoerper, guanine nucleotide binding protein (G protein), q polypeptide antikoerper, G protein subunit alpha q antikoerper, guanine nucleotide binding protein (G protein), q polypeptide S homeolog antikoerper, guanine nucleotide binding protein, alpha q polypeptide antikoerper, gnaq antikoerper, GNAQ antikoerper, Gnaq antikoerper, gnaq.S antikoerper
- Hintergrund
- Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta.Synonyms: GAQ, Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein alpha-q
- Gen-ID
- 2776
- NCBI Accession
- NP_002063
- UniProt
- P50148
- Pathways
- JAK-STAT Signalweg, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction
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