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Plakophilin 2 Antikörper (Internal Region)
PKP2
Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh)
WB, EIA
Wirt: Ziege
Polyclonal
unconjugated
Produktdetails anti-Plakophilin 2 Antikörper
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Target
Alle Plakophilin 2 (PKP2) Antikörper anzeigen
Plakophilin 2 (PKP2)
Bindungsspezifität
Alle Epitope für Plakophilin 2 Antikörper
AA 125-139, Internal Region
Reaktivität
Alle Reaktivitäten für Plakophilin 2 Antikörper
Human, Ratte, Maus, Hund, Rind (Kuh)
Wirt
Alle Wirte für Plakophilin 2 Antikörper
Ziege
Klonalität
Alle Klonalitäten für Plakophilin 2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für Plakophilin 2 Antikörper
Dieser Plakophilin 2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Plakophilin 2 Antikörper
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequenz
C-RGTAQYSSQK SVEER
Spezifität
This antibody is expected to recognize both reported isoforms (NP_001005242.2, NP_004563.2).
Kreuzreaktivität (Details)
Species reactivity (expected):Human, Canine (Dog), Cow. Species reactivity (tested):Mouse and Rat.
Aufreinigung
Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
Immunogen
Peptide with sequence from the internal region of the protein sequence according to NP_001005242.2, NP_004563.2. Genename: PKP2
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Discover our top product PKP2 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu Plakophilin 2
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Target
Plakophilin 2 (PKP2)
Andere Bezeichnung
Plakophilin-2 (PKP2 Produkte )
Synonyme
ARVD9 antikoerper, 1200008D14Rik antikoerper, 1200012P04Rik antikoerper, AA516617 antikoerper, Pkp2l antikoerper, plakophilin 2 antikoerper, PKP2 antikoerper, Pkp2 antikoerper
Hintergrund
Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 1 mediates increases in desmosomal protein content, desmosome assembly and regulation of cell migration. Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Plakophilin 4 is a component of desmosomal adhesion plaques that regulates junctional plaque organization and cadherin function.Synonyms: PKP2
Gen-ID
5318
NCBI Accession
NP_004563
UniProt
Q99959
Pathways
Cell-Cell Junction Organization , SARS-CoV-2 Protein Interaktom , Phosphorylierungen bei SARS-CoV-2 Infektion
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