Plakophilin 1 Antikörper (N-Term) (CF®405S)

Produktnummer ABIN6166943

Produktdetails anti-Plakophilin 1 Antikörper (CF®405S)

Target: Plakophilin 1 (PKP1)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Plakophilin 1 Antikörper ist konjugiert mit CF®405S

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Verwendungszweck: Mouse Monoclonal anti-Plakophilin-1 (10B2), CF405S Conjugate

Produktmerkmale: This antibody recognizes a protein of 75 kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: N-terminus of human Plakophilin-1 protein (exact sequence is proprietary)

Klon: 10B2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry 0.5-1 μg/million cells/0.1 mL

• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

HaCat Cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu Plakophilin 1

Target: Plakophilin 1 (PKP1)

Andere Bezeichnung: Plakophilin-1 (PKP1 Produkte)

Synonyme: PKP1 antikoerper, fb30d08 antikoerper, wu:fb30d08 antikoerper, AI528551 antikoerper, B6P antikoerper, plakophilin 1 antikoerper, plakophilin 1b antikoerper, PKP1 antikoerper, pkp1b antikoerper, Pkp1 antikoerper

Hintergrund: B6P, B, 6 protein, PKP1, Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome)

Molekulargewicht: 75 kDa

Gen-ID: 5317, 497350

UniProt: Q13835