CD37 Antikörper
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- Target Alle CD37 (TSPAN26) Antikörper anzeigen
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD37 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Verwendungszweck
- Mouse Monoclonal anti-CD37 (IPO-24), Purified, with BSA
- Produktmerkmale
- This antibody recognizes a protein of 33-55 kDa, identified as CD37 (Workshop V, Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg ) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Aufreinigung
- Purified
- Immunogen
- Spleen cells of a patient with hairy cell leukemia
- Klon
- IPO-24
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product TSPAN26 Primärantikörper
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- Applikationshinweise
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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Daudi, Raji, Namalva, Ramos cells and human lymphocytes. Human tonsil and lymph node.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 200 μg/mL
- Buffer
- PBS/0.05 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
- Andere Bezeichnung
- CD37 (TSPAN26 Produkte)
- Synonyme
- Tspan26 antikoerper, GP52-40 antikoerper, TSPAN26 antikoerper, CD37 antigen antikoerper, CD37 molecule antikoerper, Cd37 antikoerper, CD37 antikoerper
- Hintergrund
- Cell differentiation antigen 37, GP52 40, Tetraspanin-26, Tspan-26, TSPAN26
- Molekulargewicht
- 33-55 kDa
- Gen-ID
- 951, 166556
- UniProt
- P11049
- Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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