Nkx2-2 Antikörper (CF®594)
-
- Target Alle Nkx2-2 Antikörper anzeigen
- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
-
Reaktivität
- Human, Maus, Ratte, Huhn
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Nkx2-2 Antikörper ist konjugiert mit CF®594
-
Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Verwendungszweck
- Mouse Monoclonal anti-NKX2.2 (NX2/294), CF594 Conjugate
- Produktmerkmale
- Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Human full-length recombinant NKX2.2 protein
- Klon
- NX2-294
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product Nkx2-2 Primärantikörper
-
-
- Applikationshinweise
-
Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
-
Pancreas or Ewing s sarcoma
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
-
- Target
- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
- Andere Bezeichnung
- NKX2.2 (Nkx2-2 Produkte)
- Synonyme
- XeNK-2 antikoerper, Xnkx2.2 antikoerper, nkx2-2-A antikoerper, nkx2.2 antikoerper, NKX-2.2 antikoerper, NKX2.2 antikoerper, NKX2B antikoerper, Nkx-2.2 antikoerper, Nkx2.2 antikoerper, tinman antikoerper, id:ibd5090 antikoerper, nk2.2 antikoerper, nkx2-2 antikoerper, wu:fc83b01 antikoerper, zgc:136536 antikoerper, NK2 homeobox 2 S homeolog antikoerper, NK2 homeobox 2 antikoerper, NK2 homeobox 2a antikoerper, nkx2-2.S antikoerper, NKX2-2 antikoerper, Nkx2-2 antikoerper, nkx2.2a antikoerper
- Hintergrund
- Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman
- Molekulargewicht
- 40-50 kDa
- Gen-ID
- 4821, 516922
- UniProt
- O95096
- Pathways
- Dopaminergic Neurogenesis
-