PAX6 Antikörper (N-Term) (CF®488A)
-
- Target Alle PAX6 Antikörper anzeigen
- PAX6 (Paired Box 6 (PAX6))
-
Bindungsspezifität
- AA 1-300, N-Term
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser PAX6 Antikörper ist konjugiert mit CF®488A
-
Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Verwendungszweck
- Mouse Monoclonal anti-PAX6 (PAX6/1166), CF488A Conjugate
- Produktmerkmale
- Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant fragment (N-terminus, aa 1-300) of human PAX6 protein
- Klon
- PAX6-1166
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product PAX6 Primärantikörper
-
-
- Applikationshinweise
-
Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
-
Pancreas, Cerebellum or Stomach
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
-
- Target
- PAX6 (Paired Box 6 (PAX6))
- Andere Bezeichnung
- PAX6 (PAX6 Produkte)
- Synonyme
- pax6 antikoerper, an2 antikoerper, mgda antikoerper, wagr antikoerper, pax-6 antikoerper, pax6a antikoerper, xpax6 antikoerper, XLPAX6 antikoerper, MGC52531 antikoerper, PAX-6 antikoerper, AN antikoerper, AN2 antikoerper, D11S812E antikoerper, MGDA antikoerper, WAGR antikoerper, Pax-6 antikoerper, pax6b antikoerper, 1500038E17Rik antikoerper, AEY11 antikoerper, Dey antikoerper, Gsfaey11 antikoerper, Sey antikoerper, PAXZF-A antikoerper, Pax6.1 antikoerper, cb280 antikoerper, fc20e07 antikoerper, pax-a antikoerper, pax[zf-a] antikoerper, paxzfa antikoerper, wu:fc20e07 antikoerper, zfpax-6a antikoerper, zfpax-6b antikoerper, paired box 6 antikoerper, paired box 6 L homeolog antikoerper, paired box 6 S homeolog antikoerper, paired box 6a antikoerper, PAX6 antikoerper, pax6 antikoerper, Pax6 antikoerper, pax6.L antikoerper, pax6.S antikoerper, pax6a antikoerper
- Hintergrund
- AN2, Aniridia type II protein, Oculorhombin, Paired box gene 6 (aniridia keratitis), Paired box homeotic gene 6, Paired box protein Pax-6, Sey, WAGR
- Molekulargewicht
- 47 kDa
- Gen-ID
- 5080, 611376
- UniProt
- P26367
- Pathways
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
-