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Fibrillarin Antikörper

FBL Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3021515
  • Target Alle Fibrillarin (FBL) Antikörper anzeigen
    Fibrillarin (FBL)
    Reaktivität
    • 50
    • 30
    • 29
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 43
    • 10
    • 1
    Kaninchen
    Klonalität
    • 42
    • 12
    Polyklonal
    Konjugat
    • 33
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Fibrillarin Antikörper ist unkonjugiert
    Applikation
    • 45
    • 12
    • 11
    • 10
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human FBL
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C/-80 °C
  • Zheng, Xiong, Wu, Chen, Chen, Fleming, Gao, Bi, Ge: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).

  • Target
    Fibrillarin (FBL)
    Andere Bezeichnung
    FBL (FBL Produkte)
    Hintergrund
    Fibrillarin is a 2-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place. Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2-O-ribose methylation of targeted nucleotides within the rRNA sequence. The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development.
    Synonyms: FBL, FIB, FLRN, RNU3IP1
    Gen-ID
    2091
    UniProt
    P22087
    Pathways
    Ribonucleoside Biosynthetic Process
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