MUTYH Antikörper
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- Target Alle MUTYH Antikörper anzeigen
- MUTYH (MutY Homolog (E. Coli) (MUTYH))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MUTYH Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of human MUTYH
- Isotyp
- IgG
- Top Product
- Discover our top product MUTYH Primärantikörper
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- Applikationshinweise
- Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid freeze / thaw cycles
- Lagerung
- -20 °C/-80 °C
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- Target
- MUTYH (MutY Homolog (E. Coli) (MUTYH))
- Andere Bezeichnung
- MUTYH (MUTYH Produkte)
- Synonyme
- MUTYH antikoerper, MGC145569 antikoerper, CYP2C antikoerper, MYH antikoerper, 5730495A01Rik antikoerper, Mutyha antikoerper, Mutyhalpha antikoerper, Mutyhb antikoerper, Mutyhbeta antikoerper, Mutyhc antikoerper, Myh antikoerper, mutY DNA glycosylase antikoerper, mutY homolog (E. coli) antikoerper, A/G-specific adenine DNA glycosylase-like antikoerper, MUTYH antikoerper, mutyh antikoerper, LOC100373318 antikoerper, Mutyh antikoerper
- Hintergrund
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Base excision repair (BER) proteins catalyze the removal of incorrect or damaged bases, including oxidized bases, from DNA. N-glycosylases specific to a given lesion remove the incorrect base as the first step in BER. MYH is the mammalian ortholog of E. coli MutY, a DNA glycosylase that catalyzes the removal of 8-oxoG:A mismatches. Several MYH isoforms have been detected in human cells localizing to either the nucleus or the mitochondria. MYH interacts with DNA repair proteins and localizes to DNA damage foci after oxidative damage. Research studies have shown that mutations in the corresponding MYH gene are associated with human gastric and colorectal cancers.
Synonyms: MGC4416, MYH - Gen-ID
- 4595
- UniProt
- Q9UIF7
- Pathways
- DNA Reparatur
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