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PTEN Antikörper (pThr401)

PTEN Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB39432 unconjugated
Produktnummer ABIN6241054
  • Target Alle PTEN Antikörper anzeigen
    PTEN (Phosphatase and Tensin Homolog (PTEN))
    Bindungsspezifität
    • 19
    • 18
    • 18
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr401
    Reaktivität
    • 59
    • 23
    • 21
    • 5
    • 4
    • 2
    • 2
    • 2
    Human
    Wirt
    • 58
    • 1
    Kaninchen
    Klonalität
    • 57
    • 2
    Polyklonal
    Konjugat
    • 44
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PTEN Antikörper ist unkonjugiert
    Applikation
    • 36
    • 20
    • 19
    • 14
    • 14
    • 13
    • 11
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Dot Blot (DB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PTEN Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T401 of human PTEN.
    Klon
    RB39432
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PTEN Primärantikörper
  • Applikationshinweise
    DB: 1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    PTEN (Phosphatase and Tensin Homolog (PTEN))
    Andere Bezeichnung
    PTEN (PTEN Produkte)
    Synonyme
    10q23del antikoerper, BZS antikoerper, CWS1 antikoerper, DEC antikoerper, GLM2 antikoerper, MHAM antikoerper, MMAC1 antikoerper, PTEN1 antikoerper, TEP1 antikoerper, 2310035O07Rik antikoerper, A130070J02Rik antikoerper, AI463227 antikoerper, B430203M17Rik antikoerper, Mmac antikoerper, PTENP1 antikoerper, wu:fc52g04 antikoerper, zgc:73086 antikoerper, fa11a08 antikoerper, fb73f10 antikoerper, fc83f12 antikoerper, fd16b10 antikoerper, fk90e11 antikoerper, pten antikoerper, si:bz1g13.4 antikoerper, wu:fa11a08 antikoerper, wu:fb73f10 antikoerper, wu:fc83f12 antikoerper, wu:fd16b10 antikoerper, wu:fk90e11 antikoerper, phosphatase and tensin homolog antikoerper, phosphatase and tensin homolog L homeolog antikoerper, phosphatase and tensin homolog A antikoerper, phosphatase and tensin homolog B antikoerper, PTEN antikoerper, Pten antikoerper, pten.L antikoerper, ptena antikoerper, ptenb antikoerper
    Hintergrund
    This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
    Molekulargewicht
    47166
    NCBI Accession
    NP_000305
    UniProt
    P60484
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Inositol Metabolic Process, Synaptic Membrane, Regulation of Cell Size, Autophagie, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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