RAD9A Antikörper
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- Target Alle RAD9A Antikörper anzeigen
- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
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Reaktivität
- Human, Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser RAD9A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Immunogen
- Recombinant Protein
- Top Product
- Discover our top product RAD9A Primärantikörper
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anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 162-391) antibody
RAD9A Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (Center) antibodyRAD9A Reaktivität: Human, Maus, Ratte WB, IHC (p), IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (pSer328) antibodyRAD9A Reaktivität: Human WB, IHC (p), DB Wirt: Kaninchen Polyclonal RB7115 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) antibodyRAD9A Reaktivität: Human, Affe, Hund WB, IHC, IHC (p) Wirt: Maus Monoclonal 5D9 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 365-391) antibodyRAD9A Reaktivität: Human WB, IHC (p), IF Wirt: Kaninchen Polyclonal RB29524 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (pSer272) antibodyRAD9A Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB7109 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 1-30) antibodyRAD9A Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB0965-RB0966 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 264-370) antibodyRAD9A Reaktivität: Human, Maus, Ratte WB, IF Wirt: Maus Monoclonal 56-hRad9 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 267-341) antibodyRAD9A Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (C-Term) antibodyRAD9A Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- IP: 1:500. WB: 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Lagerung
- 4 °C,-20 °C
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- Target
- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
- Andere Bezeichnung
- RAD9A (RAD9A Produkte)
- Synonyme
- RAD9 antikoerper, Rad9 antikoerper, rad9a antikoerper, MGC89062 antikoerper, XRad9 antikoerper, rad9 antikoerper, RAD9 checkpoint clamp component A antikoerper, RAD9 checkpoint clamp component B antikoerper, RAD9 checkpoint clamp component A L homeolog antikoerper, RAD9A antikoerper, Rad9a antikoerper, rad9a antikoerper, rad9b antikoerper, rad9a.L antikoerper
- Hintergrund
- Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds, endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths, and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3'->5' double stranded DNA exonuclease activity. Its phosphorylation by PRKCD may be required for the formation of the 9-1-1 complex.
- UniProt
- Q99638
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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