CBX3 Antikörper
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- Target Alle CBX3 Antikörper anzeigen
- CBX3 (Chromobox Homolog 3 (CBX3))
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Reaktivität
- Human, Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CBX3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- Immunogen
- Recombinant Protein
- Top Product
- Discover our top product CBX3 Primärantikörper
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- Applikationshinweise
- IP: 1:500. WB: 1:1000. IHC: 1:100. ICC: 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Lagerung
- 4 °C,-20 °C
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- Target
- CBX3 (Chromobox Homolog 3 (CBX3))
- Andere Bezeichnung
- HP1-gamma (CBX3 Produkte)
- Hintergrund
- Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the mehtyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.
- UniProt
- Q13185
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