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NEIL3 Antikörper

NEIL3 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6241838
  • Target Alle NEIL3 Antikörper anzeigen
    NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 22
    • 2
    Kaninchen
    Klonalität
    • 22
    • 2
    Polyklonal
    Konjugat
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser NEIL3 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 16
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Immunogen
    synthetic peptide
    Top Product
    Discover our top product NEIL3 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Lagerung
    4 °C,-20 °C
  • Target
    NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))
    Andere Bezeichnung
    NEIL3 (NEIL3 Produkte)
    Synonyme
    RGD1310562 antikoerper, NEIL3 antikoerper, zgc:103553 antikoerper, neil3 antikoerper, MAC12.12 antikoerper, MAC12_12 antikoerper, FGP2 antikoerper, FPG2 antikoerper, NEI3 antikoerper, hFPG2 antikoerper, hNEI3 antikoerper, AI449477 antikoerper, BC034753 antikoerper, C85903 antikoerper, nei-like DNA glycosylase 3 antikoerper, nei like DNA glycosylase 3 antikoerper, GRF zinc finger / Zinc knuckle protein antikoerper, nei-like DNA glycosylase 3 L homeolog antikoerper, nei like 3 (E. coli) antikoerper, Neil3 antikoerper, NEIL3 antikoerper, neil3 antikoerper, AT5G13920 antikoerper, neil3.L antikoerper
    Hintergrund
    DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA, also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5- OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.
    UniProt
    Q8TAT5
    Pathways
    DNA Reparatur
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