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HGS Antikörper

HGS Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6241891
  • Target Alle HGS Antikörper anzeigen
    HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))
    Reaktivität
    • 44
    • 30
    • 21
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 38
    • 5
    • 1
    Kaninchen
    Klonalität
    • 41
    • 3
    Polyklonal
    Konjugat
    • 32
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HGS Antikörper ist unkonjugiert
    Applikation
    • 36
    • 21
    • 19
    • 15
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Immunogen
    Synthetic Peptide
    Top Product
    Discover our top product HGS Primärantikörper
  • Applikationshinweise
    IF: 1:100. WB: 1:1000. IHC: 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Lagerung
    4 °C,-20 °C
  • Target
    HGS (Hepatocyte Growth Factor-Regulated tyrosine Kinase Substrate (HGS))
    Andere Bezeichnung
    HGS (HGS Produkte)
    Synonyme
    HRS antikoerper, Hrs antikoerper, fi34f05 antikoerper, zgc:63492 antikoerper, wu:fi34f05 antikoerper, Hgr antikoerper, ZFYVE8 antikoerper, CG2903 antikoerper, Dmel\\CG2903 antikoerper, HRS-2 antikoerper, Vps27 antikoerper, hrs antikoerper, l(2)23AB5 antikoerper, l(2)23Ad antikoerper, l(2)23Ad(Hrs) antikoerper, vps27 antikoerper, hgs antikoerper, hepatocyte growth factor-regulated tyrosine kinase substrate antikoerper, HGF-regulated tyrosine kinase substrate antikoerper, Hepatocyte growth factor regulated tyrosine kinase substrate antikoerper, hepatocyte growth factor-regulated tyrosine kinase substrate L homeolog antikoerper, HGS antikoerper, Hgs antikoerper, hgs antikoerper, Hrs antikoerper, hgs.L antikoerper
    Hintergrund
    Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down- regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. May contribute to the efficient recruitment of SMADs to the activin receptor complex. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation.
    UniProt
    O14964
    Pathways
    EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Synaptic Vesicle Exocytosis, EGFR Downregulation
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