NFE4 Antikörper (C-Term)

Produktnummer ABIN6242126

Produktdetails anti-NFE4 Antikörper

Target: NFE4 (Transcription Factor NF-E4 (NFE4))

Bindungsspezifität: AA 135-169, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFE4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NFE4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 135-169 amino acids from the C-terminal region of human NFE4.

Klon: RB51299

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu NFE4

Target: NFE4 (Transcription Factor NF-E4 (NFE4))

Andere Bezeichnung: NFE4 (NFE4 Produkte)

Synonyme: NF-E4 antikoerper, nuclear factor, erythroid 4 antikoerper, NFE4 antikoerper

Hintergrund: Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR). The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma- globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.

Molekulargewicht: 19019

UniProt: Q86UQ8