ANAPC2 Antikörper (C-Term)

Produktnummer ABIN6242188

Produktdetails anti-ANAPC2 Antikörper

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Bindungsspezifität: AA 712-746, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANAPC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ANAPC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 712-746 amino acids from the C-terminal region of human ANAPC2.

Klon: RB51676

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:25. WB: 1:1000. IHC-P: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu ANAPC2

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Andere Bezeichnung: ANAPC2 (ANAPC2 Produkte)

Synonyme: anapc2 antikoerper, ANAPC2 antikoerper, DDBDRAFT_0203816 antikoerper, DDBDRAFT_0234264 antikoerper, DDB_0203816 antikoerper, DDB_0234264 antikoerper, si:ch73-203i15.5 antikoerper, APC2 antikoerper, RP11-350O14.5 antikoerper, 9230107K09Rik antikoerper, AL024279 antikoerper, Apc2 antikoerper, Emi4 antikoerper, Imi4 antikoerper, mKIAA1406 antikoerper, F28I8.30 antikoerper, F28I8_30 antikoerper, anaphase-promoting complex/cyclosome 2 antikoerper, anaphase promoting complex subunit 2 antikoerper, anaphase promoting complex subunit 2 L homeolog antikoerper, anaphase-promoting complex/cyclosome 2 antikoerper, Anaphase-promoting complex subunit 2 antikoerper, ANAPC2 antikoerper, anapc2.L antikoerper, anapc2 antikoerper, Anapc2 antikoerper, APC2 antikoerper, apc-2 antikoerper

Hintergrund: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.

Molekulargewicht: 93828

UniProt: Q9UJX6

Pathways: Regulation of Cell Size