Aurora Kinase C Antikörper (C-Term)

Produktnummer ABIN6242197

Dieses Anti-Aurora Kinase C-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Aurora Kinase C in WB und IHC (p). Geeignet für Human.

Kurzübersicht für Aurora Kinase C Antikörper (C-Term) (ABIN6242197)

Target: Aurora Kinase C (AURKC)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aurora Kinase C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB0881

Produktdetails anti-Aurora Kinase C Antikörper

Bindungsspezifität: C-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Aurora-C (AURKC) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region with lysine at position 255 of human AURKC.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu Aurora Kinase C

Target: Aurora Kinase C (AURKC)

Andere Bezeichnung: Aurora-C (AURKC)

Hintergrund: Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.

Molekulargewicht: 35591

NCBI Accession: NP_001015878, NP_001015879, NP_003151

UniProt: Q9UQB9

Pathways: Zellzyklus, Maintenance of Protein Location