This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This (DANRE) tie2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 160-194 amino acids from the N-terminal region of DANRE tie2.
TEK antikoerper, DKFZp469E064 antikoerper, AA517024 antikoerper, Cd202b antikoerper, Hyk antikoerper, Tie2 antikoerper, tie-2 antikoerper, CD202B antikoerper, TIE-2 antikoerper, TIE2 antikoerper, VMCM antikoerper, VMCM1 antikoerper, Tie-2 antikoerper, tie2 antikoerper, TEK receptor tyrosine kinase antikoerper, angiopoietin-1 receptor antikoerper, TEK tyrosine kinase, endothelial antikoerper, TEK antikoerper, LOC100408334 antikoerper, tek antikoerper, Tek antikoerper
Hintergrund
Tyrosine-protein kinase that acts as cell-surface receptor for angiopoietins and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Can activate or inhibit angiogenesis, depending on the context. Angiopoietin signaling triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors (By similarity).