DMBT1 Antikörper (AA 2160-2192)

Produktnummer ABIN6242287

Produktdetails anti-DMBT1 Antikörper

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Bindungsspezifität: AA 2160-2192

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMBT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DMBT1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2160-2192 amino acids from human DMBT1.

Klon: RB53896

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu DMBT1

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Andere Bezeichnung: DMBT1 (DMBT1 Produkte)

Synonyme: GP340 antikoerper, muclin antikoerper, CRP antikoerper, CRP-[a] antikoerper, CRP-[b] antikoerper, Crpd antikoerper, DBMT1 antikoerper, gp300 antikoerper, p80 antikoerper, DMBT1 antikoerper, gp340 antikoerper, deleted in malignant brain tumors 1 antikoerper, deleted in malignant brain tumors 1 protein antikoerper, gp340 antikoerper, deleted in malignant brain tumors 1 S homeolog antikoerper, DMBT1 antikoerper, Dmbt1 antikoerper, LOC100064515 antikoerper, dmbt1 antikoerper, ST201phi2-1p340 antikoerper, dmbt1.S antikoerper

Hintergrund: May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. May function as a binding protein in saliva for the regulation of taste sensation. Binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly- sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH -dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell.

Molekulargewicht: 260735

UniProt: Q9UGM3

Pathways: Activation of Innate immune Response