Drosophila SUMO (N-Term) Antikörper

Produktnummer ABIN6242330

Produktdetails

Target: Drosophila SUMO

Bindungsspezifität: N-Term

Reaktivität: Drosophila melanogaster, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Bitte anfragen

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Drosophila SUMO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Drosophila SUMO1.

Klon: RB3486

Isotyp: Ig Fraction

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen

Matsui, Sharma, Cooke, Wakimoto, Rasool, Hayworth, Hylton, Tomkiel: "Nuclear structure and chromosome segregation in Drosophila male meiosis depend on the ubiquitin ligase dTopors." in: Genetics, Vol. 189, Issue 3, pp. 779-93, (2012) (PubMed).

Antigendetails

Target: Drosophila SUMO

Hintergrund: Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a maternal role in anterior-posterior (A/P) polarity and patterning.

Molekulargewicht: 10124

UniProt: O97102