FOXN4 Antikörper (C-Term)
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- Target Alle FOXN4 Antikörper anzeigen
- FOXN4 (Forkhead Box N4 (FOXN4))
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Bindungsspezifität
- AA 436-470, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FOXN4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This FOXN4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 436-470 amino acids from the C-terminal region of human FOXN4.
- Klon
- RB52411
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product FOXN4 Primärantikörper
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- Applikationshinweise
- WB: 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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- Target
- FOXN4 (Forkhead Box N4 (FOXN4))
- Andere Bezeichnung
- FOXN4 (FOXN4 Produkte)
- Synonyme
- whn antikoerper, whna antikoerper, forkhead box N4 antikoerper, forkhead box N4 S homeolog antikoerper, FOXN4 antikoerper, foxn4 antikoerper, Foxn4 antikoerper, foxn4.S antikoerper
- Hintergrund
- Transcription factor essential for neural and some non- neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4- NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity).
- Molekulargewicht
- 55215
- UniProt
- Q96NZ1
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