IL-11 Antikörper (AA 27-61)
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- Target Alle IL-11 (IL11) Antikörper anzeigen
- IL-11 (IL11) (Interleukin 11 (IL11))
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Bindungsspezifität
- AA 27-61
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IL-11 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This IL11 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-61 amino acids from human IL11.
- Klon
- RB56890
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product IL11 Primärantikörper
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- Applikationshinweise
- WB: 1:2000. FC: 1:25
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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- Target
- IL-11 (IL11) (Interleukin 11 (IL11))
- Andere Bezeichnung
- IL11 (IL11 Produkte)
- Synonyme
- IL11 antikoerper, AGIF antikoerper, IL-11 antikoerper, Il-11 antikoerper, interleukin 11 antikoerper, IL11 antikoerper, Il11 antikoerper
- Hintergrund
- Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:< a href="http://www.uniprot.org/citations/2145578" target="_blank">2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:< a href="http://www.uniprot.org/citations/12919066" target="_blank">12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
- Molekulargewicht
- 21429
- UniProt
- P20809
- Pathways
- JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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