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IL-11 Antikörper (AA 27-61)

IL11 Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal RB56890 unconjugated
Produktnummer ABIN6242412
  • Target Alle IL-11 (IL11) Antikörper anzeigen
    IL-11 (IL11) (Interleukin 11 (IL11))
    Bindungsspezifität
    • 15
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 27-61
    Reaktivität
    • 47
    • 29
    • 28
    Human
    Wirt
    • 47
    • 19
    • 1
    • 1
    Kaninchen
    Klonalität
    • 48
    • 20
    Polyklonal
    Konjugat
    • 33
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL-11 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 35
    • 17
    • 13
    • 13
    • 10
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Flow Cytometry (FACS)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This IL11 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-61 amino acids from human IL11.
    Klon
    RB56890
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product IL11 Primärantikörper
  • Applikationshinweise
    WB: 1:2000. FC: 1:25
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    IL-11 (IL11) (Interleukin 11 (IL11))
    Andere Bezeichnung
    IL11 (IL11 Produkte)
    Synonyme
    IL11 antikoerper, AGIF antikoerper, IL-11 antikoerper, Il-11 antikoerper, interleukin 11 antikoerper, IL11 antikoerper, Il11 antikoerper
    Hintergrund
    Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:< a href="http://www.uniprot.org/citations/2145578" target="_blank">2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:< a href="http://www.uniprot.org/citations/12919066" target="_blank">12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
    Molekulargewicht
    21429
    UniProt
    P20809
    Pathways
    JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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