KIT Ligand Antikörper (C-Term)
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- Target Alle KIT Ligand (KITLG) Antikörper anzeigen
- KIT Ligand (KITLG)
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Bindungsspezifität
- AA 201-234, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KIT Ligand Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This KITLG antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 201-234 amino acids from the C-terminal region of human KITLG.
- Klon
- RB50736
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product KITLG Primärantikörper
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- Applikationshinweise
- WB: 1:1000. WB: 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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- Target
- KIT Ligand (KITLG)
- Andere Bezeichnung
- KITLG (KITLG Produkte)
- Synonyme
- Xkl-1 antikoerper, Xsl antikoerper, Xsl-1 antikoerper, Xsl-2 antikoerper, steel antikoerper, KITLG antikoerper, SCF antikoerper, kitl antikoerper, kl-1 antikoerper, mgf antikoerper, scf antikoerper, FPH2 antikoerper, KL-1 antikoerper, Kitl antikoerper, MGF antikoerper, SF antikoerper, SHEP7 antikoerper, Clo antikoerper, Con antikoerper, Gb antikoerper, Kitlg antikoerper, Mgf antikoerper, SLF antikoerper, Sl antikoerper, blz antikoerper, contrasted antikoerper, 710-712 antikoerper, CSF antikoerper, KITL antikoerper, KIT ligand L homeolog antikoerper, KIT ligand antikoerper, kit ligand antikoerper, kitlg.L antikoerper, KITLG antikoerper, kitlg antikoerper, Kitl antikoerper, Kitlg antikoerper
- Hintergrund
- Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5- trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.
- Molekulargewicht
- 30899
- UniProt
- P21583
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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