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MBD2 Antikörper (AA 10-228)

MBD2 Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 1812CT625-9-45 unconjugated
Produktnummer ABIN6242434
  • Target Alle MBD2 Antikörper anzeigen
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-228
    Reaktivität
    • 47
    • 23
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 45
    • 1
    • 1
    Maus
    Klonalität
    • 45
    • 2
    Monoklonal
    Konjugat
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MBD2 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 22
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This MBD2 antibody is generated from a mouse immunized with a recombinant protein between 10-228 amino acids from human MBD2.
    Klon
    1812CT625-9-45
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product MBD2 Primärantikörper
  • Applikationshinweise
    WB: 1:2000. IHC-P: 1:25
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Andere Bezeichnung
    MBD2 (MBD2 Produkte)
    Synonyme
    MBD2 antikoerper, DMTase antikoerper, NY-CO-41 antikoerper, MBD2a antikoerper, wu:fa97f06 antikoerper, zgc:111862 antikoerper, methyl-CpG binding domain protein 2 antikoerper, methyl-CpG binding domain protein 2 S homeolog antikoerper, MBD2 antikoerper, Mbd2 antikoerper, mbd2 antikoerper, mbd2.S antikoerper
    Hintergrund
    Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
    Molekulargewicht
    43255
    UniProt
    Q9UBB5
    Pathways
    Chromatin Binding
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