MBD2 Antikörper (AA 10-228)
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- Target Alle MBD2 Antikörper anzeigen
- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
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Bindungsspezifität
- AA 10-228
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MBD2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- Immunogen
- This MBD2 antibody is generated from a mouse immunized with a recombinant protein between 10-228 amino acids from human MBD2.
- Klon
- 1812CT625-9-45
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product MBD2 Primärantikörper
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- Applikationshinweise
- WB: 1:2000. IHC-P: 1:25
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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- Target
- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
- Andere Bezeichnung
- MBD2 (MBD2 Produkte)
- Synonyme
- MBD2 antikoerper, DMTase antikoerper, NY-CO-41 antikoerper, MBD2a antikoerper, wu:fa97f06 antikoerper, zgc:111862 antikoerper, methyl-CpG binding domain protein 2 antikoerper, methyl-CpG binding domain protein 2 S homeolog antikoerper, MBD2 antikoerper, Mbd2 antikoerper, mbd2 antikoerper, mbd2.S antikoerper
- Hintergrund
- Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
- Molekulargewicht
- 43255
- UniProt
- Q9UBB5
- Pathways
- Chromatin Binding
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