MLF1 Antikörper (AA 91-126)

Produktnummer ABIN6242439

Produktdetails anti-MLF1 Antikörper

Target: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Bindungsspezifität: AA 91-126

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This (Mouse) Mlf1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 91-126 amino acids from the Central region of (Mouse) Mlf1.

Klon: RB51172

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu MLF1

Target: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Andere Bezeichnung: Mlf1 (MLF1 Produkte)

Synonyme: MLF1 antikoerper, HLS7 antikoerper, myeloid leukemia factor 1 antikoerper, myeloid leukemia factor 1 L homeolog antikoerper, MLF1 antikoerper, mlf1.L antikoerper, mlf1 antikoerper, Mlf1 antikoerper

Hintergrund: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Molekulargewicht: 30432

UniProt: Q9QWV4