MED15 Antikörper (C-Term)

Produktnummer ABIN6242466

Produktdetails anti-MED15 Antikörper

Target: MED15 (Mediator Complex Subunit 15 (MED15))

Bindungsspezifität: AA 743-779, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Med15 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 743-779 amino acids from the C-terminal region of Mouse Med15.

Klon: RB51972

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu MED15

Target: MED15 (Mediator Complex Subunit 15 (MED15))

Andere Bezeichnung: Med15 (MED15 Produkte)

Hintergrund: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway (By similarity).

Molekulargewicht: 86607

UniProt: Q924H2

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha