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RAB13 Antikörper (AA 1-203)

RAB13 Reaktivität: Human WB Wirt: Maus Monoclonal 1600CT845-37-29 unconjugated
Produktnummer ABIN6242518
  • Target Alle RAB13 Antikörper anzeigen
    RAB13 (RAB13, Member RAS Oncogene Family (RAB13))
    Bindungsspezifität
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-203
    Reaktivität
    • 20
    • 14
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 16
    • 4
    Maus
    Klonalität
    • 16
    • 4
    Monoklonal
    Konjugat
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RAB13 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This RAB13 antibody is generated from a mouse immunized with a recombinant protein between 1-203 amino acids from human RAB13.
    Klon
    1600CT845-37-29
    Isotyp
    IgG1
    Top Product
    Discover our top product RAB13 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    RAB13 (RAB13, Member RAS Oncogene Family (RAB13))
    Andere Bezeichnung
    RAB13 (RAB13 Produkte)
    Synonyme
    cb764 antikoerper, hm:zeh0455 antikoerper, RAB13 antikoerper, 0610007N03Rik antikoerper, B230212B15Rik antikoerper, RAB13, member RAS oncogene family antikoerper, rab13 antikoerper, RAB13 antikoerper, Rab13 antikoerper
    Hintergrund
    The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in endocytic recycling and regulates the transport to the plasma membrane of transmembrane proteins like the tight junction protein OCLN/occludin. Thereby, it regulates the assembly and the activity of tight junctions. Moreover, it may also regulate tight junction assembly by activating the PKA signaling pathway and by reorganizing the actin cytoskeleton through the activation of the downstream effectors PRKACA and MICALL2 respectively. Through its role in tight junction assembly, may play a role in the establishment of Sertoli cell barrier. Plays also a role in angiogenesis through regulation of endothelial cells chemotaxis. Also involved in neurite outgrowth. Has also been proposed to play a role in post-Golgi membrane trafficking from the TGN to the recycling endosome. Finally, it has been involved in insulin- induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore may play a role in glucose homeostasis.
    Molekulargewicht
    22774
    UniProt
    P51153
    Pathways
    Cell-Cell Junction Organization
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