RNF139 Antikörper (AA 604-636)
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- Target Alle RNF139 Antikörper anzeigen
- RNF139 (Ring Finger Protein 139 (RNF139))
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Bindungsspezifität
- AA 604-636
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RNF139 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This RNF139 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 604-636 amino acids from human RNF139.
- Klon
- RB54248
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product RNF139 Primärantikörper
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- Applikationshinweise
- WB: 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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- Target
- RNF139 (Ring Finger Protein 139 (RNF139))
- Andere Bezeichnung
- RNF139 (RNF139 Produkte)
- Synonyme
- HRCA1 antikoerper, RCA1 antikoerper, TRC8 antikoerper, 4930555P18Rik antikoerper, zgc:175173 antikoerper, rnf139 antikoerper, ring finger protein 139 antikoerper, ring finger protein 139 S homeolog antikoerper, RNF139 antikoerper, Rnf139 antikoerper, rnf139 antikoerper, rnf139.S antikoerper
- Hintergrund
- E3-ubiquitin ligase, acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor.
- Molekulargewicht
- 75994
- UniProt
- Q8WU17
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