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RAD9A Antikörper (N-Term)

RAD9A Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB52362 unconjugated
Produktnummer ABIN6242554
  • Target Alle RAD9A Antikörper anzeigen
    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
    Bindungsspezifität
    • 22
    • 15
    • 15
    • 15
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-62, N-Term
    Reaktivität
    • 148
    • 48
    • 23
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 158
    • 10
    • 1
    Kaninchen
    Klonalität
    • 159
    • 10
    Polyklonal
    Konjugat
    • 70
    • 15
    • 13
    • 12
    • 10
    • 10
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RAD9A Antikörper ist unkonjugiert
    Applikation
    • 137
    • 82
    • 54
    • 41
    • 40
    • 29
    • 13
    • 10
    • 9
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This mouse Rad9a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 29-62 amino acids from the N-terminal region of mouse Rad9a.
    Klon
    RB52362
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product RAD9A Primärantikörper
  • Applikationshinweise
    WB: 1:2000. WB: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
    Andere Bezeichnung
    Rad9a (RAD9A Produkte)
    Synonyme
    RAD9 antikoerper, Rad9 antikoerper, rad9a antikoerper, MGC89062 antikoerper, XRad9 antikoerper, rad9 antikoerper, RAD9 checkpoint clamp component A antikoerper, RAD9 checkpoint clamp component B antikoerper, RAD9 checkpoint clamp component A L homeolog antikoerper, RAD9A antikoerper, Rad9a antikoerper, rad9a antikoerper, rad9b antikoerper, rad9a.L antikoerper
    Hintergrund
    Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds, endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths, and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3'->5' double stranded DNA exonuclease activity (By similarity).
    Molekulargewicht
    42059
    UniProt
    Q9Z0F6
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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