TNIK Antikörper (Ser764)

Produktnummer ABIN6242564

Produktdetails anti-TNIK Antikörper

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Bindungsspezifität: Ser764

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNIK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNIK(S764) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human TNIK(S764).

Klon: RB59089

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500. WB: 1:500. IHC-P-Leica: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu TNIK

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Andere Bezeichnung: TNIK (TNIK Produkte)

Synonyme: RGD1561817 antikoerper, TNIK antikoerper, 1500031A17Rik antikoerper, 4831440I19Rik antikoerper, AI451411 antikoerper, C530008O15Rik antikoerper, C630040K21Rik antikoerper, fc52d11 antikoerper, msn antikoerper, tnikl antikoerper, wu:fc52d11 antikoerper, zgc:63535 antikoerper, im:6898857 antikoerper, zgc:123033 antikoerper, zgc:152783 antikoerper, tnik antikoerper, TRAF2 and NCK interacting kinase antikoerper, TRAF2 and NCK interacting kinase a antikoerper, TRAF2 and NCK interacting kinase b antikoerper, TRAF2 and NCK interacting kinase S homeolog antikoerper, TNIK antikoerper, Tnik antikoerper, tnika antikoerper, tnikb antikoerper, tnik.S antikoerper

Hintergrund: Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.

Molekulargewicht: 154943

UniProt: Q9UKE5