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TNIK Antikörper (Ser764)

TNIK Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB59089 unconjugated
Produktnummer ABIN6242564
  • Target Alle TNIK Antikörper anzeigen
    TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
    Bindungsspezifität
    • 24
    • 15
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser764
    Reaktivität
    • 58
    • 53
    • 38
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 85
    • 4
    Kaninchen
    Klonalität
    • 85
    • 4
    Polyklonal
    Konjugat
    • 36
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TNIK Antikörper ist unkonjugiert
    Applikation
    • 36
    • 31
    • 27
    • 27
    • 18
    • 16
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This TNIK(S764) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human TNIK(S764).
    Klon
    RB59089
    Isotyp
    IgG
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  • Applikationshinweise
    WB: 1:500. WB: 1:500. IHC-P-Leica: 1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Target
    TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
    Andere Bezeichnung
    TNIK (TNIK Produkte)
    Hintergrund
    Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
    Molekulargewicht
    154943
    UniProt
    Q9UKE5
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